The activity of this theme concern the development of microbial bioprocesses, the bioprocesses of animal cell culture and also the enzymatic bioprocesses. In order to develop in a rational way the most performing new bioprocesses, the whole of the research activity integrate both the experimental and numerical aspects on:
(i) the cell environment thanks to the macroscopic and the microscopic kinetic studies under controlled culture systems;
ii) the conception and the study of reactors for the biotransformation in order to obtain a fine comprehension of the effect of the environment on the performance of biocatalyst;
iii) the characterisation of reactional processes involved in order to control the obtention of active molecules of desired quality.
- Aerobial microbial bioprocesses for the metabolite production for the chemical industry (synthons), pharmaceutics (antibiotics) or for energy (hydrogen, methane).
- Bioprocesses of animal cell culture for the production of therapeutic proteins (antibody) or stem cells (produced cells)
- On-line spectroscopic analysis (NIR, RAMAN, di-electrical)
- Enzymatic bioprocesses of acylation of aminoacids, peptides and phenolic compounds.