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Accueil du site > Présentation > Productions scientifiques

Publications 2016

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PUBLICATIONS 2016 - LRGP

[hal-01510237] Detailed kinetic modeling of the formation of toxic polycyclic aromatic hydrocarbons (PAHs) coming from pyrolysis in low-pressure gas carburizing conditions

21 avril 2017

Hydrocarbon pyrolysis in low-pressure gas carburizing conditions leads to gas phase reactions, which produce polycyclic aromatic hydrocarbons (PAHs), some of which, such as benzo[a]pyrene, are carcinogenic. Workers can be exposed to these PAHs during maintenance and cleaning operations of (...)

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[hal-01507492] Treatment of highly concentrated tannery wastewater using electrocoagulation: Influence of the quality of aluminium used for the electrode

14 avril 2017

This paper deals with the ability of electrocoagulation (EC) to remove simultaneously COD and chromium from a real chrome tanning wastewater in a batch stirred electro-coagulation cell provided with two aluminium-based electrodes (aluminium/copper/magnesium alloy and pure aluminium). Effects of (...)

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[hal-01501367] Enzymatic bioreactor for simultaneous electrosynthesis and energy production

5 avril 2017

The proof-of-concept for enzymatic electrosynthesis with simultaneous energy production has been demonstrated by using the regioselective conversion of D-sorbitol to D-fructose by D-sorbitol dehydrogenase as a model reaction. The bioreactor was composed of two electrodes, a carbon felt bioanode (...)

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[hal-01498467] PDTeam’s project : Targeting to improve PDT selectivity

30 mars 2017

Since 15 years, our main goal consists in improving the selectivity of PDT treatment. Different strategies are developed in Nancy by the PDTeam. The ability to directly target a therapeutic agent to a tumoral site minimizes systemic drug exposure, thus providing the potential for increasing the (...)

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[hal-01498318] Pseudopeptide bioconjugate additives for CO 2 separation membranes

30 mars 2017

1:1[α/α-Nα-Bn-hydrazino] pseudopeptide−polymer bioconjugates were synthesized and investigated as additives in a reference gas separation membrane (Pebax®) for CO2 capture. Pebax® is a polyether block amide thermoplastic elastomer provided by Arkema and is already well known for its good performance (...)

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[hal-01498155] Chronic impact of sulfamethoxazole on the metabolic activity and composition of enriched nitrifying microbial culture

29 mars 2017

This study investigated the chronic impact of sulfamethoxazole (SMX) on activated sludge sustaining an enriched nitrifying biomass. For this purpose, a laboratory scale fill and draw reactor was operated with 100 mg COD/L of peptone mixture and 50 mg N/L of ammonia at a sludge age of 15 days. (...)

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[hal-01497721] Response surface methodology applied to Supercritical Fluid Extraction (SFE) of carotenoids from Persimmon (Diospyros kaki L.)

29 mars 2017

Supercritical carbon dioxide with ethanol as co-solvent was used to extract carotenoids from persimmon fruits (Diospyros kaki L.). Based on a response surface methodology (RSM), a predicting model describing the effects of CO2 temperature, pressure, flow rate, ethanol percentage and extraction (...)

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[hal-01497719] Stability of folic acid under several parameters

29 mars 2017

Folic acid is a small molecule, also known as vitamin B-9. It is an essential compound involved in important biochemical processes. It is widely used as a vector for targeted treatment and diagnosis especially in cancer therapeutics. Nevertheless, not many authors address the problem of folic (...)

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[hal-01497716] Application of Raman Spectroscopy to Characterization of Residence Time Distribution and Online Monitoring of a Pilot-Scale Tubular Reactor for Acrylic Acid Solution Polymerization

29 mars 2017

A pilot-scale tubular reactor containing static mixers is equipped with several Raman probes in order to perform online monitoring of radical copolymerization of acrylic acid in aqueous solution. This setup allows determination of residence time distribution while polymerization reaction (...)

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[hal-01497715] On the Modeling of Acrylic Acid Copolymerization in an Aqueous Solution: A Modular, Integrated Approach

29 mars 2017

A complete mathematical model of the free-radical copolymerization of acrylic acid in an aqueous solution, taking place in a pilot-scale tubular reactor equipped with static mixers, is presented. The developed kinetic/reactor model is numerically integrated in terms of a coupled (...)

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[hal-01496660] Driving Forces Controlling Host-Guest Recognition in Supercritical Carbon Dioxide Solvent.

28 mars 2017

The formation of supramolecular host-guest complexes is a very useful and widely employed tool in chemistry. However, supramolecular chemistry in non-conventional solvents such as supercritical carbon dioxide (scCO2 ), one of the most promising sustainable solvents, is still in its infancy. In (...)

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[tel-01492968] Étude des procédés d’amplification de cellules souches mésenchymateuses humaines

21 mars 2017

L'essor des thérapies régénératives au cours des 10 dernières années a entraîné un effort de recherche important, mais l'obtention des cellules souches humaines en quantité suffisante reste cependant encore problématique, notamment concernant les cellules souches mésenchymateuses (CSM). Ces travaux ont (...)

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[tel-01487017] Détoxification des eaux usées urbaines par photocatalyse solaire

11 mars 2017

Ces dernières décennies, la pollution de l’eau est devenue un problème se posant avec insistance dans le monde entier. En effet, la forte croissance des besoins en eau due à l’accroissement démographique ainsi qu’aux évolutions industrielles, agricoles et urbaines, engendrent des quantités énormes de (...)

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[tel-01470491] Design of targeted photosensitizer-conjugates towards Neuropilin-1 and folate receptors for improving the selectivity of anti-cancer photodynamic therapy

22 février 2017

Photodynamic therapy (PDT) is a type of cancer therapy that could offer many advantages. One possible way to improve the effectiveness of PDT is the elaboration of third generation photosensitizers (PSs) which consisted of PSs coupled with targeting agents. This thesis focuses on improving the (...)

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[hal-01433850] Diethyl ether pyrolysis study in a jet-stirred reactor

19 janvier 2017

This paper reports new experimental measurements for the pyrolysis of diethyl ether at temperatures between 600 and 1100 K under dilute conditions. This work was performed using a jet-stirred reactor at pressures from 26.7 kPa (200 Torr) to 107.7 kPa (800 Torr) with dilution in helium, for (...)

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[hal-01416493] Effect of Potassium on the Mechanisms of Biomass Pyrolysis Studied using Complementary Analytical Techniques

15 décembre 2016

Complementary analytical methods have been used to study the effect of potassium on the pyrolysis mechanisms of cellulose and lignocellulosic biomasses. Thermogravimetry, calorimetry, high-temperature (1) H NMR spectroscopy (in situ and real-time analysis of the fluid phase formed during (...)

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[hal-01414783] Thermal cracking of 1-n-butyldecalin at high pressure (100bar)

12 décembre 2016

The pyrolysis of 1-n-butyldecalin at high pressure (100 bar) was studied in gold sealed tube reactors at 400 °C. It leads to 4 main chemical families of products in order of predominance: (a) normal alkanes (methane, ethane, propane and n-butane), (b) bicyclics (decalin and 1-methyldecalin), (c) (...)

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[hal-01413873] A consistency test for α-functions of cubic equations of state

12 décembre 2016

This study highlights that α-functions used in cubic equations of state must be of class C2 i.e. that their first and second derivatives must exist and must be continuous, positive , monotonically decreasing , convex and also verify , for any value of the temperature T. Our proposed “consistency (...)

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[hal-01408942] Overview of existing Langevin models formalism for heavy particle dispersion in a turbulent channel flow

8 décembre 2016

The purpose of the paper is to compare two successful families of stochastic model for the prediction of inertial particles dispersion in a turbulent channel flow. Both models are based on the Langevin equation; nevertheless, they were developed following different paths. The first model (...)

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[hal-01410295] Less-Nafion electrodes based on PSSA-Pt/Vulcan catalyst for PEM fuel cells

8 décembre 2016

Functionalization on the carbon material of PEM fuel cells providing them an ionic conductivity, has been thought as a promising way to improve the catalyst activity. Pt/Vulcan catalysts grafted with polystyrene sulfonate (PSSA) groups from 5 to 20 wt.% have been prepared. Owing to the (...)

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[hal-01409977] Electrocatalytic activity enhancement of a graphene ink-coated carbon cloth cathode for oxidative treatment

7 décembre 2016

A new graphene-based cathode for electro-Fenton (EF) treatment of wastewater was developed by graphene-ink coating on carbon cloth. Electrochemical exfoliation led to graphene sheet resistance 6-fold lower than a conventional chemical method, an improvement which was attributed to the higher (...)

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[hal-01400682] The LOFT mission concept: a status update

7 décembre 2016

The Large Observatory For x-ray Timing (LOFT) is a mission concept which was proposed to ESA as M3 and M4 candidate in the framework of the Cosmic Vision 2015-2025 program. Thanks to the unprecedented combination of effective area and spectral resolution of its main instrument and the uniquely (...)

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[hal-01406702] Life cycle assessment of agromining chain highlights role of erosion control and bioenergy

6 décembre 2016

Agromining is the recovery of valuable heavy metals from soils with high metal concentrations, using hyperaccumulator plants, to produce value added products. It allows the exploitation of low-grade ores for which conventional mining techniques are too expensive and detrimental to the (...)

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[hal-01406740] Pericyclic Reactions in Ether Biofuels

6 décembre 2016

Unimolecular decompositions of acyclic ethers through a pericyclic mechanism, i.e., alcohol elimination, have been shown to play a crucial role in the high-temperature combustion of these compounds. The production of new fuels derived from biomass has led to a renewed interest into the (...)

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[hal-01264846] Inorganic nanoparticles for photodynamic therapy

1er décembre 2016

Photodynamic therapy (PDT) is a well-established technique employed to treat aged macular degeneration and certain types of cancer, or to kill microbes by using a photoactivatable molecule (a photosensitizer, PS) combined with light of an appropriate wavelength and oxygen. Many PSs are used (...)

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[hal-01382160] Increasing purity of ammonium nickel sulfatehexahydrate and production sustainability in a nickel phytomining process

22 novembre 2016

Phytomining, now called agromining, consists of growing hyperaccumulator plants in orderto farm metals and recover them from the biomass. This technology enables us to extractmetals from secondary resources (e.g. metal containing-soils, mineral wastes, polluted soils)and manufacture high-value (...)

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[hal-01263587] Agromining for nickel: a complete chain that optimizes ecosystem services rendered by ultramafic landscapes.

21 novembre 2016

Serpentine (i.e. ultramafic) outcrops in Europe cover more than 10,000 km2 and have a low-fertility and low-productivity, making them unattractive for traditional agriculture. In general, these areas are slowly abandoned by local farmers, affected by strong rural exodus and landscapes undergo a (...)

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[hal-01304140] Increasing purity of ammonium nickel sulfate hexahydrate and production sustainability in a nickel phytomining process

21 novembre 2016

Phytomining, now called agromining, consists of growing hyperaccumulator plants in order to farm metals and recover them from the biomass. This technology enables us to extract metals from secondary resources (e.g. metal containing-soils, mineral wastes, polluted soils) and manufacture (...)

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[hal-01259752] Increasing purity of ammonium nickel sulfatehexahydrate and production sustainability in anickel phytomining process

21 novembre 2016

Phytomining, now called agromining, consists of growing hyperaccumulator plants in orderto farm metals and recover them from the biomass. This technology enables us to extractmetals from secondary resources (e.g. metal containing-soils, mineral wastes, polluted soils)and manufacture high-value (...)

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[hal-01399256] Proton MR spectroscopy and diffusion MR imaging monitoring to predict tumor response to interstitial photodynamic therapy for glioblastoma

20 novembre 2016

Despite recent progress in conventional therapeutic approaches, the vast majority of glioblastoma recur locally, indicating that a more aggressive local therapy is required. Interstitial photodynamic therapy (iPDT) appears as a very promising and complementary approach to conventional (...)

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[hal-01205739] Realtime tracking of the Photobleaching Trajectory during Photodynamic Therapy

18 novembre 2016

Photodynamic therapy (PDT) is an alternative treatment for cancer that involves the administration of a photosensitizing agent, which is activated by light at a specific wavelength. This illumination causes after a sequence of photoreactions, the production of reactive oxygen species (...)

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[insu-01351256] Imaging Jupiter’s radiation belts down to 127 MHz with LOFAR

3 novembre 2016

Context. Observing Jupiter's synchrotron emission from the Earth remains today the sole method to scrutinize the distribution and dynamical behavior of the ultra energetic electrons magnetically trapped around the planet (because in-situ particle data are limited in the inner magnetosphere). (...)

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[insu-01321898] LOFAR MSSS: detection of a low-frequency radio transient in 400 h of monitoring of the North Celestial Pole

3 novembre 2016

We present the results of a four-month campaign searching for low-frequency radio transients near the North Celestial Pole with the Low-Frequency Array (LOFAR), as part of the Multifrequency Snapshot Sky Survey (MSSS). The data were recorded between 2011 December and 2012 April and comprised (...)

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[hal-01387444] Fluid phase equilibria prediction of fluorocompound-containing binary systems with the predictive E-PPR78 model

29 octobre 2016

In order to reduce the overall emissions of greenhouse gases and to be in compliance with the current environmental regulations, a new class of refrigerants, making use of fluorocompounds has appeared. Such refrigerants are often blends of alkanes, CO 2 and fluorocompounds. Consequently an (...)

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[hal-01388370] Influence de la stabilité et de la photoréactivité sur la toxicité des nanoparticules : cas de l'oxyde de zinc ZnO

27 octobre 2016

Ces dernières années, les énormes progrès réalisés en nanotechnologie ainsi qu’en science des matériaux ont conduit à la synthèse de nombreuses nouvelles nanoparticules sans réellement connaître l’ensemble des propriétés et des risques associés à leurs dimensions. L’oxyde de zinc ZnO sous forme (...)

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[hal-01241520] Prediction of auto-ignition temperatures and delays for gas turbine applications

24 octobre 2016

Gas turbines burn a large variety of gaseous fuels under elevated pressure and temperature conditions. During transient operations, variable gas/air mixtures are involved in the gas piping system. In order to predict the risk of auto-ignition events and ensure a safe operation of gas turbines, (...)

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[hal-01382653] New trends in photodynamic therapy

21 octobre 2016

The aim of my talk is to present different strategies that have been developed to take up the challenges of photodynamic therapy in the research field (red or NIR absorption, targeting, nanoparticles…) and to develop particular cases emerging from our lab (...)

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[hal-01384360] Continuous Pilot-Scale Tubular Reactor for Acrylic Acid Polymerization in Solution Designed Using Lab-Scale Rheo-Raman data

20 octobre 2016

A continuous pilot-scale tubular reactor is designed for the polymerization of acrylic acid in aqueous solution. The reactor is equipped with CSE-X static mixers from Fluitec which strongly increase heat and mass transfer despite laminar flow. A mathematical model of the reactor is proposed (...)

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[hal-01276589] Symptomatic Profiles of Patients With Polycythemia Vera: Implications of Inadequately Controlled Disease.

12 octobre 2016

Polycythemia vera (PV) is a myeloproliferative neoplasm (MPN) associated with disabling symptoms and a heightened risk of life-threatening complications. Recent studies have demonstrated the effectiveness of JAK inhibitor therapy in patients with PV patients who have a history of prior (...)

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[hal-01349641] Steam reforming of methane in a synthesis gas from biomass gasification

5 octobre 2016

An experimental and modelling study of the pyrolysis and of the steam reforming of methane in mixtures representative of a gas produced from biomass gasification has been performed. The experimental study has been done in a plug flow reactor under a near atmospheric pressure (1.07 bar), for a (...)

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[hal-01371730] High performance Ce-doped ZnO nanorods for sunlight-driven photocatalysis

27 septembre 2016

Ce-doped ZnO (ZnO:Ce) nanorods have been prepared through a solvothermal method and the effects of Ce-doping on the structural, optical and electronic properties of ZnO rods were studied. ZnO:Ce rods were characterized by XRD, SEM, TEM, XPS, BET, DRS and Raman spectroscopy. 5% Ce-doped ZnO rods (...)

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[hal-01372065] Gold Nanoparticles Grafted by Reduced Glutathione With Thiol Function Preservation

27 septembre 2016

Gold nanoparticles (AuNP) are one of the most widely applied nanomaterials for biomedical purposes due to their ease of preparation,well-defined structure and simple surface functionalization.Herein, a method to anchor reduced glutathione (GSH, i.e. an important antioxidant tripeptide in all (...)

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[hal-01349454] An updated experimental and kinetic modeling study of n-heptane oxidation

2 août 2016

This work presents an updated experimental and kinetic modeling study of n-heptane oxidation. In the experiments, ignition delay times of stoichiometric n-heptane/air mixtures have been measured in two different high-pressure shock tubes in the temperature range of 726–1412 K and at elevated (...)

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[hal-01349463] Understanding the reactivity of unsaturated alcohols: Experimental and kinetic modeling study of the pyrolysis and oxidation of 3-methyl-2-butenol and 3-methyl-3-butenol

2 août 2016

The reactivity of unsaturated alcohols with a C=C double bond in the β- and γ-positions to the hydroxyl group is not well established. The pyrolysis and oxidation of two such unsaturated alcohols have been studied, i.e. 3-methyl-2-butenol (prenol) and 3-methyl-3-butenol (isoprenol). Experiments (...)

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[hal-01343605] Recent developments in photocatalytic applications design of graphene-based or doped ZnO photocatalysts

9 juillet 2016

Semiconductor mediated photocatalysis is an efficient method for environmental detoxification, which is able of converting toxic and nonbiodegradable organic compounds into carbon dioxide, water and inorganic salts. Zinc oxide ZnO is one of the most promising photocatalyst both for solar energy (...)

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[hal-01342449] iRGD peptide as effective transporter of CuInZnxS2+x quantum dots into human cancer cells

7 juillet 2016

In this paper, iRGD peptide-mediated quantum dots (QDs) delivery was studied. In the first step,dodecanethiol-capped CuInZnxS2 x (ZCIS) QDs were prepared and subsequently transferred into water using a standard and facile ligand exchange approach involving 3-mercaptopropionic acid (MPA). (...)

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[hal-01327392] High temperature rheological study of borosilicate glasses containing platinum group metal particles by means of a mixer-type rheometer

7 juin 2016

In this paper, the rheological behavior of six simulated high level waste nuclear glasses containing 0 to 5.2 wt% platinum group metals (PGM) has been studied at a temperature of 1200 °C. By means of a stress imposed rheometer, the shear stress dependence of the viscosity, which was so far (...)

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[hal-01323038] Ethyl biodiesel production from non-edible oils of Balanites aegyptiaca, Azadirachta indica, and Jatropha curcas seeds - Laboratory scale development

31 mai 2016

By starting first at the laboratory scale, optimal operating conditions for the reaction unit aimed at producing ethyl biodiesels from non-edible vegetable oils (NEVO) were determined with the ultimate objective of proposing an on-farm processing technology that should be sustainable for (...)

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[hal-01297727] Aqueous synthesis of Cu-doped CdZnS quantum dots with controlled and efficient photoluminescence

11 mai 2016

We report here a facile, mild and low cost aqueous-based synthesis for the production of high quality CdZnS and Cu-doped CdZnS quantum dots (QDs). We demonstrate that the photoluminescence (PL) of the Cu-doped CdZnS nanocrystals could be tuned in the whole visible spectrum via the (...)

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[hal-01303879] Porous Mn-doped ZnO nanoparticles for enhanced solar and visible light photocatalysis

10 mai 2016

Porous Mn-doped ZnO (ZnO:Mn) nanoparticles with an average diameter of ca. 21 nm were prepared by a simple and cheap solvothermal process involving no templates, post-synthetic annealing or etching. The particles produced were characterized by XRD, Raman spectroscopy, SEM, TEM, XPS, diffuse (...)

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[hal-01293012] What kind of modern “green” chemical engineering is required for the design of the “factory of future”?

10 mai 2016

Confronted with the globalization of the markets, acceleration of partnerships and innovation, and to offer a contribution to the fight against environmental destruction and non sustainable behaviour of the today world production, the chemical and related industries militate for the evolution (...)

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[hal-01264845] Corrosion inhibition of carbon steel in acidic medium by orange peel extract and its main antioxidant compounds

10 mai 2016

Chemical compounds of orange peel extracts were identified and their antioxidant activities were determined. The inhibiting effect on acidic steel corrosion brought by the extract and selected antioxidant compounds (neohesperidin, naringin, ascorbic acid) was evaluated separately by (...)

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[hal-01309306] Molecular modelling, synthesis and biological evaluation of peptide inhibitors as anti-angiogenic agent targeting Neuropilin-1 for anticancer application

10 mai 2016

VEGF and its co-receptor neuropilin-1 (NRP-1) are important targets of many pro-angiogenic factors. In this study, nine peptides were synthesized and evaluated for their molecular interaction with NRP-1 and compared to our previous peptide ATWLPPR. Docking study showed that the investigated (...)

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[hal-01296623] Good modelling practice in applying computational fluid dynamics for WWTP modelling

10 mai 2016

Computational fluid dynamics (CFD) modelling in the wastewater treatment (WWT) field is continuing to grow and be used to solve increasingly complex problems. However, the future of CFD models and their value to the wastewater field are a function of their proper application and knowledge of (...)

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[hal-01288737] Production of singlet Oxygen by nanoparticle-bound photosensitizers

10 mai 2016

New improvements in the field of targeted PDT concern the use of nanoparticles that can serve as carriers for anticancer agent delivery. Nanoparticles do indeed offer many advantages such as good colloidal stability, effective protection of encapsulated drugs against enzymes and hydrolysis, (...)

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[hal-01304884] Experimental and modeling investigation of the effect of the unsaturation degree on the gas-phase oxidation of fatty acid methyl esters found in biodiesel fuels

10 mai 2016

The oxidation of three C19 fatty acid methyl esters present in biodiesel fuel was experimentally investigated using a jet-stirred reactor in order to highlight the effect of double bonds on the reactivity and product distribution. Fuel candidates were methyl-stearate, methyl oleate and methyl (...)

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[hal-01305110] Study of the Formation of the First Aromatic Rings in the Pyrolysis of Cyclopentene

10 mai 2016

The thermal decomposition of cyclopentene was studied in a jet-stirred reactor operated at constant pressure and temperature to provide new experimental information about the formation of the first aromatic rings from cyclic C5 species. Experiments were carried out at a residence time of 1 s, a (...)

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[hal-01299823] Peptide-functionalized ZCIS QDs as fluorescent nanoprobe for targeted HER2-positive breast cancer cells imaging

10 mai 2016

In this paper, the synthesis of alloyed CuInZnxS2+x quantum dots (ZCIS QDs), their transfer into aqueous solution via a polymer coating technique, and the use of these nanocrystals to selectively target HER2- positive cells, are reported. By optimizing first the ZnS shell deposition process (...)

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[hal-01293425] Intensification of phosphate removal using electrocoagulation treatment by continuous pH adjustment and optimal electrode connection mode

10 mai 2016

This paper discusses two possible ways of intensifying the electrocoagulation treatment of water contg. phosphate. The first one consists of controlling the chem. compn. of the water by continuous adjustment of the pH. The second aspect focuses on electrode connection modes, and the four (...)

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[hal-01278688] Breakup Dynamics for High-Viscosity Droplet Formation in a Flow-Focusing Device: Symmetrical and Asymmetrical Ruptures

10 mai 2016

The breakup mechanism of high-viscosity thread for droplet formation in a flow-focusing device is investigated using a high-speed digital camera. Aqueous solution of 89.5%-glycerol is used as the dispersed phase, while silicone oil as the continuous phase. The breakup process of the dispersed (...)

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[hal-01278687] A concept of reactive compatibilizer-tracer for studying reactive polymer blending processes

10 mai 2016

Significance A concept called reactive compatibilizer-tracer is proposed. The latter bears reactive groups capable of reacting with its counterpart on forming a copolymer for in situ compatibilization, and fluorescent labels allowing determining very small amounts of the in situ formed (...)

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